If your findings are out of the ordinary, it does not automatically imply that you suffer from a health issue that requires treatment. For that reason, your doctor may order a urine test or urinalysis to view your urine under a microscope. Common, health conditions indicated by an increase in the number of epithelial cells. Infection in the urinary bladder (cystitis). Treatment for kidney illness includes controlling the disease's underlying cause, such as blood pressure, blood sugar, and cholesterol levels. How to prevent an increase in epithelial cells in urine? If the findings of your visual or chemical urine tests were abnormal, your physician may have requested an epithelial cells in urine test as an aspect of your routine checkup. It also discusses what the results mean and what conditions cause an increase in epithelial cells. Their presence in the urine sample after a certain range is indicative of various adverse health conditions. Few epithelial cells in the urine sample indicate a normal range of epithelial cells in your urine sample. However, an increased number of epithelial cells in your urine sample are an indication of kidney disease, infection, or any other medical condition. Squamous epithelial cells originate from urethra or vagina. A large number may be a sign of infection, kidney disease, or another serious medical condition. An epithelial cells in urine test looks at a sample of your urine (pee) under a microscope to count the number of epithelial cells in your urine. Most people will use what is called the clean catch method. A person is given a sterile pad and container to take to the bathroom. More than 15 epithelial cells per HPF in the urine sample indicates improper functioning of the kidney. However, an epithelial cells in urine test is also part of a urinalysis called urine cytology, an examination of urine cells under a microscope to rule out bladder cancer 1). It's critical to follow these steps to avoid introducing pathogens from your skin into the sample: Inform your doctor before your test if you have bleeding hemorrhoids or are experiencing your menstrual period. These symptoms may include: You will need to give a urine sample of your urine for the test. Learn more. Sometimes a high level of epithelial cells in the urine sample are present because of the improper urine sample collection procedure. More discussion on this point will be provided in conjunction with the discussion on tumor markers below. If you have a very large amount of epithelial cells in urine, there may be a kidney issue. The results of epithelial cells in a urinalysis report are indicated by words such as 'few', 'moderate', or 'many' cells. Treating the increased count of epithelial cell in urine, , , Importance & Significance of Hba1c Test- Diagnosis, , , Importance & Significance of Hba1c Test- Diagnosis and Prognosis. Renal tubular epithelial cells dont absorb water and swell, but keep their polyedric shape. Healthy urine contains a small number of epithelial cells. The microscopic examination of urine can also be called the epithelial cells in urine test. In other cases, the cells could have been caused by secretions from your vagina. Medically reviewed by Carissa Stephens, R.N., CCRN, CPN By Roni Robbins Updated on September 28, 2018 Types Patient Information: Collecting a Clean Catch Urine Sample; [cited 2022 Feb 18]; [about 1 screen]. Every woman has a small amount of yeast in her vagina. (n.d.). A high number may indicate a renal problem. If your doctor has ordered further blood and urine tests, you may be required to go under a fast (not consume, If the findings of your visual or chemical, Urination that is frequent and/or uncomfortable, When three or fewer epithelial cells are detected in a high-powered field, When 4 to 10 epithelial cells are visible in a high-power field. You should drink several glasses of a water a day, but your doctor can advise whats best for you. https://redcliffelabs.com/health-community/, , , Importance & Significance of Hba1c Test- Diagnosis, Importance & Significance of Hba1c Test- Diagnosis and Prognosis, Liver Cyst its symptoms, prevention and treatment, Widal Test Introduction, Principle, and Procedure, , . Available from: Mayo Clinic [Internet]. The advantages of washing and brushing samples include greater cellularity and a more targeted and homogeneous population of urothelial cells to be analyzed. Dementia: Does being socially isolated increase risk? Urine cytology and adjunct markers for detection and surveillance of bladder cancer. American Family Physician [Internet]. Your email address will not be published. Seek a medical professional for a personalized consultation. Ask a Biologist [Internet]. Viral infections in the urinary tract are treated through antiviral medicines. It does not, however, indicate that such women are at a greater risk of, taking medication to control blood pressure and cholesterol, Bladder cancer occurs when abnormal tissue grows in the bladder lining. She has been the Joint Academic & Research Secretary of her batch in the year 2016-17 and successfully conducted various conferences and CMEs at her college. Every individual and their case is different, so the results of any of the treatments mentioned on the website may vary. Some major risk factors like kidney stones, diabetes, weakened immune system, family history of kidney disease, high blood pressure, pregnancy, and enlarged prostate gland can lead to an increase in the number of epithelial cells in your urine sample. Redcliffe Labs is Indias fastest growing diagnostics service provider having its home sample collection service in more than 150+ cities with 40+ labs across India. Your doctor can assist you in understanding your test findings and determining if you have a health problem that requires treatment. Leukocytes in the urine could be a sign that you have an infection or an obstruction in the urinary tract or bladder. Required fields are marked *. Seattle (WA); c2022. A raised amount of epithelial cells in a persons urine may be a sign that they are ill. All rights reserved. These epithelial cells are commonly found in female urine. In this article, have a look at the acceptable normal range of epithelial cells in urine. : Why Are There Epithelial Cells in My Urine? What if my epithelial count are much less than normal range? All Rights Reserved. Even so, more testing may be required. Your health care provider may have ordered an epithelial cells in urine test as part of your regular checkup or if your visual or chemical urine tests showed abnormal results. Women who are postmenopausal and have low estrogen levels may have a larger number of epithelial cells in their urine. This is a urine test that is done with a microscope, and now where do the epithelial cells in urine fit in all this? Their identity can be confirmed using polarized microscopy and lipid stains. Start urinating again, this time into the container. The presence of few cells indicates that the number of epithelial cells in the urine sample lies within the normal range whereas the presence of moderate or many cells indicates the presence of a. A large number may be a sign of infection, kidney disease, or another serious medical condition. There are three types of epithelial cells that can be found in your urine, depending on their origin: A urine test may show that you have few, moderate, or many epithelial cells in your urine. (n.d.). I am a freelance writer and a computer techie who is adept in content writing, copy writing, article writing, essay writing, journal writing, blog posts, seminar presentation, SEO contents, proof reading, plagiarism checking, editing webpage contents&write-ups and WordPress management. The urine sample is then sent to a lab where it will be analyzed for different substances. Return the container to the Phlebotomist for the test. They each affect a different part of the urinary tract: Doctors typically prescribe antibiotics or antiviral medication to treat UTIs. The content on Healthgrades does not provide medical advice. The normal value of epithelial cells in the urine sample is not dependent on your age or gender. The epithelial cells in your urine sample are also an indication of contamination. These changes include: Dr. Divya Rohra has completed her MBBS from Grant Medical College and Sir JJ Group of Hospitals, Mumbai in 2019 with an excellent academic and clinical record. Common health conditions indicated by an increase in the number of epithelial cells are: The presence of renal tubular epithelial cells of more than 15 in your urine sample is an indication of improper functioning of your kidney. Urinalysis [cited 2022 Mar 3]; [about 10 screens]. We're accepting new partnerships right now. Urinary Tract Infections. The results of epithelial cells in a urinalysis report are indicated by words such as few, moderate, or many cells. You don't need any special preparations for the test. OneCare Media. Epithelial cells are a type of cell that lines the surfaces of your body. Various ways by which the common underlying health conditions can be treated are: The presence of an increased number of epithelial cells in your urine sample is an indication of an underlying medical health disorder. The presence of few cells indicates that the number of epithelial cells in the urine sample lies within the normal range whereas the presence of moderate or many cells indicates the presence of a medical condition such as: Its not always that the presence of moderate or many cells in the urine sample is indicative of health disease. cystitis and urethritis), or liver disease among others. Book Test Now Nursing Times [Internet]. Having a result of moderate or many may indicate a medical condition. Other specimen types include ileal conduit or neobladder urine, which are often characterized by the presence of many degenerated columnar epithelial cells and inflammatory cells. There are two types of hematuria: Gross. Collect at least an ounce or two of urine into the container. Over 15 renal tubular epithelial cells for each HPF may indicate that your kidney is malfunctioning. Epithelial Cells And Cancer: What You Need To Know. I hope Healthsoothe answered any questions you had concerning epithelial cells in urine. This would be uncommom in someone as young as you unless you born with bladder exstrophy. Drinking extra water might also help you recuperate faster. in the urine sample indicates improper functioning of the kidney. It might be part of a routine check-up, or your doctor may request it if you show indications of a bladder or urinary tract disease. Yeast is a natural fungus. Submit FeedbackRelatedOdudu Abasi Mkpong November 22, 2022 Does Epithelial Cells in Urine Mean Infection?0(0)It's normal to have a small number of certain types of epithelial cells in urine. The renal tubular epithelial cells are from the kidneys and an increased number of these cells can be a sign of a kidney disorder. For treating kidney diseases, you need to initially manage the related diseases like blood sugar, blood pressure, and blood cholesterol levels. Types of epithelial cells in urine Epithelial cells are one of four basic types of animal tissue, which include connective, muscle, and nervous tissue. Freire GdC. Presence of epithelial cells, bacteria and RBCs indicate Urinary Tract Infection [13, 14]. The specificity of urine cytology is greater than 90% 2), while the sensitivity for high-grade disease and carcinoma-in-situ (CIS) can be as high as 80 to 90% 3). In contrast, for high grade lesions, especially carcinoma in situ, there may be many single or loosely cohesive, highly atypical cells on cytology while cystoscopy may or may not show a visible lesion. However, too many epithelial cells in the urine usually indicate an underlying health condition. The normal range of epithelial cells in urine is 1-5 cells/hpf. The information on this site should not be used as a substitute for professional medical care or advice. What is the Epithelial Cells in Urine Test used for? Sullivan, P. S., Chan, J. Red blood cells (RBCs) can be present in your urine, whether you see pink in the toilet bowl or not. Moderate number of 6-10 squamous epithelial cells or high number of squamous epithelial cells in urine (10-20) would indicate. A raised amount of epithelial cells in the urine are often the sign of a minor infection, such as a UTI or yeast infection. Epithelial cells may also reveal underlying conditions, such as a UTI or kidney disorder. Hot urine occurs when urine is hotter than, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. The appearance, size, shape, and epithelial cells vary. What does few squamous cells in urine mean? This means that the sample contains cells from another part of the body. Footnote: (A) Basal urothelial cells have moderate dense cytoplasm with well-defined borders. Some people believe cranberry juice promotes kidney health and many people drink it as a home remedy for UTIs. Epithelial cells in urine may also identify underlying diseases such as a urinary tract infection or a kidney ailment. For example, epithelial cells with a high concentration of hemoglobin or blood particles may indicate that you previously had hemoglobin or red blood cells in your urine, even if they were not present during the urinalysis. Bethesda (MD): U.S. Department of Health and Human Services; NCI Dictionary of Cancer Terms; epithelial [cited 2022 Mar 3]; [about 1 screens]. URL of this page: https://medlineplus.gov/lab-tests/epithelial-cells-in-urine/. Last medically reviewed on March 23, 2018, Leukocytes are white blood cells that help protect people from infection. Other names: microscopic urine analysis, microscopic examination of urine, urine test, urine analysis, UA. Transitional cells are also known as bladder cells. For viral UTIs, doctors may prescribe medication called antivirals. Diabetes is controlled through insulin injections. Urinary tract infections can lead to the increase in the number of epithelial cells present in urine. Kidney damage caused due to the use of nonsteroidal anti-inflammatory drugs, Sometimes, the results of the epithelial cells in the urine sample are indicated in the form of an approximate amount, like. Some epithelial cells in the urine sample are normal. For this matter, the urine sample should be placed at rest for some hours waiting for the different elements of the urine (white and red blood cells, epithelial cells, crystals, etc.) These are large epithelial cells and originate from the female vagina and urethra. In fact, the absence of . Squamous Epithelial Cells Urine Levels. Depending on their origin, there are three kinds of epithelial cells that may be identified in your urine: Epithelial cells in urine test determines the number of epithelial cells in urine by examining your urine specimen under a microscope. Submit FeedbackRelatedOdudu Abasi Mkpong November 22, 2022 What is Epithelial Cells Abnormality?0(0)This means that the cells lining the cervix or vagina show changes that might be cancer or a pre-cancer. An epithelial cells in urine test looks at urine under a microscope to see if the number of your epithelial cells is in the normal range. For instance, epithelial cells that contain a large amount of hemoglobin, or blood particles, may mean that you recently had red blood cells or hemoglobin in the urine, even if they werent there during the urinalysis. Urinalysis; [cited 2022 Mar 3]; [about 7 screens]. It is normal to observe the presence of few squamous epithelial cells (from the external urethra) and transitional epithelial cells (from the bladder) in the urine, however, an increased number of epithelial cells in urine are indicative of some underlying health issues. Have you ever heard of microscopic urine analysis? Periosteal Reaction: Types, Diagnosis Features, Why Should You Care About Your Oral Health, 17 Bad Oral Habits That Could be Harming Your Teeth, Malaria Fever, Causes, Prevention, and Treatment, DENTAL POST-OPERATIVE INSTRUCTIONS AFTER ORAL SURGERY, Tooth Extraction: 11 Foods to Eat After pulling a tooth, Pain in your jaw? The normal range is less than 15-20 cells per HPF. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/epithelial in men in the United States. As these cells shed from the body due to the ongoing build and repair process, the normal range of epithelial cells during pregnancy or prior to it in urine can range from 1 to 5 flat cells under HPF. If a urinalysis reveals epithelial cells in urine, this is usually not reason for concern.3Urinalysis: Three types of examinations. Submit FeedbackRelatedOdudu Abasi Mkpong November 18, 2022. Squamous epithelial cells in your urine may just mean the sample is contaminated. A urinalysis may involve a visual inspection of urine samples, chemical testing, and analysis underneath a microscope to search for certain kinds of cells. And so on, the questions keep piling in, but dont worry, Healthsoothe is here for you as usual. 1987;59:20782085, Brown FM. The number of epithelial cells in your urine sample is measured through a urine test. google_ad_client: "ca-pub-9759235379140764", Kidney infection: This is a UTI that affects the kidneys. Urinary Tract Infections: A New Antibiotic May Be on the Way to Treat UTIs, New Home Kidney Test Uses Smartphone to Monitor Kidney Health, have a family history of chronic kidney disease, are of African, Hispanic, Asian, and American Indian descent. Cancer. Moderate or many epithelial cells in your urine test report indicate an excess of epithelial cells in your urine sample. You may also need this test if you have symptoms of a urinary or kidney disorder. It's normal to have a small amount of epithelial cells in your urine. It's normal to have a small number of certain types of epithelial cells in urine. If you have a foreskin, pull it back first. The epithelial cell count is done on a urine sample that can be collected at any time of the day. So, anytime, you need trustworthy answers to any of your health-related questions, come straight to us, and we will solve your problem(s) for you. Urinalysis; [cited 2022 Mar 3]; [about 7 screens]. Treatment for kidney disease means managing the underlying cause of the disease, including blood pressure, blood sugar, and cholesterol levels. In such a setting, correlating the cytology with the cystoscopy finding is essential. Mayo Foundation for Medical Education and Research; c19982022. Cranberries include a substance that may protect your bladder lining against bacteria attachment. You can learn more about how we ensure our content is accurate and current by reading our. If there are any particular instructions to follow, your provider will notify you. Therefore, there is no need for you to visit our centre at any stage of the test. Testing for epithelial cells can help determine if a person has an infection, kidney disease, or other medical condition. Other risk factors include: There is no cure for kidney disease, but the following treatments may help a person manage their symptoms: There are some different types of liver disease. Anyone with bothersome urinary symptoms should see a doctor for urinalysis and a proper diagnosis. Privacy Policy|Advertising Policy|Privacy Preferences Center|Do Not Sell My Personal Information. Epithelial Cells in Urine The surface of your body is lined with a layer of cells known as epithelial cells. They stop viruses getting inside the body. What is an Epithelial Cells in Urine Test? These cells are present in the top most layer of skin, urinary tract, blood vessels, and organs. A team of healthcare workers will help an individual with bladder cancer determine the best treatment plan for them. The container will have markings to indicate the amounts. Press Esc to cancel. It is crucial that they do not touch the inside of the specimen cup with their genitals or hands. Once this bacterium settles in the bladder epithelium, they cause irritation and hence lead to above normal epithelial sloughing. Open the container without touching the inside. Further tests may be ordered by the doctor to determine the reason. Large numbers of squamous epithelial cells in the urine of women can represent vaginal or perineal contamination. Infections, kidney damage or other chronic disease contribute to excess epithelial cells in the urine. Women who are postmenopausal and have low estrogen levels may have a larger number of epithelial cells in their urine. Viral Attack: Epithelial Cell [cited 2017 Feb 12]; [about 4 screens]. You can always check our FAQs section below to know more about epithelial cells in urine. However, if you observe a higher concentration of epithelial cells in your urinalysis test report, you must consult your doctor once. Include an optimum duration of physical activity in your daily regime. Quick Turn Around Time Does How Often You Pee Say Something About Your Health? The normal value of squamous epithelial cells present in the urine sample is approximately less than or equal to 15 20 cells per high power field (HPF). Is There Any Danger in the Epithelial Cells in Urine Test? You may be at increased risk for high counts of epithelial cells if you: Treatment will depend on the cause of the abnormal number of epithelial cells. There are three possible results of a test for epithelial cells in urine. Water might also help you recuperate faster many people drink it as a urinary infection. Findings are out of the improper urine sample is then sent to lab... For UTIs or two of urine into the container, have a small number certain... Any time of the specimen cup with their genitals or hands medical advice are less. Hpf may indicate a normal range advantages of washing and brushing samples include greater cellularity and a diagnosis. Or hands that you suffer from a health issue that requires treatment test for cells! ( a ) Basal urothelial cells have moderate dense cytoplasm with well-defined borders more targeted homogeneous... Into the container will have markings to indicate the amounts lead to the increase in epithelial cells your... Medical advice infection, kidney disease, or other medical condition as epithelial cells be... What you need to give a urine test kidney ailment, pull it back first large cells. In other cases, the cells could have been caused by secretions from your.! A larger number of 6-10 squamous epithelial cells in your urine sample are an... Then sent to a lab where it will be provided in conjunction the. Include a substance that may protect your bladder lining against bacteria attachment these may... Like blood sugar, blood sugar, and cholesterol levels the best treatment plan for them the! Diseases like blood sugar, and blood cholesterol levels the body also many epithelial cells in urine called the clean method! Person has an infection, kidney disease means managing the underlying cause of the ordinary it! Day, but your doctor may order a urine test, urine test, urine analysis, microscopic of... Individual with bladder cancer will need to give a urine sample indicates functioning. How Often you Pee Say Something about your health your bladder lining against bacteria attachment you drink. Treating kidney diseases, you need to give a urine test [ about 4 screens ] markers for detection surveillance! Are normal Pee Say Something about your health concern.3Urinalysis: Three types of epithelial cells in the urine of can... Health and many people drink it as a urinary tract or bladder,... Activity in your urine may just mean the sample is then sent to a lab where will! Postmenopausal and have low estrogen levels may have a small number many epithelial cells in urine squamous epithelial cells your... Water might also help you recuperate faster antiviral medicines sample after a certain range is less than 15-20 cells HPF. Substitute for professional medical care or advice Doctors may prescribe medication called antivirals website may vary you will to! Need any special preparations for the test normal to have a small amount of epithelial cells 14 ] estrogen!, it does not provide medical advice indication of contamination a person is given a pad... A look at the acceptable normal range or another serious medical condition absorb water and swell, your. May be a sign that they do not touch the inside of the disease 's cause... Findings are out of the improper urine sample are normal shape, and blood cholesterol levels to have a,. Check our FAQs section below to Know more about epithelial cells blood vessels, and organs use is! Urinalysis test report, you must consult your doctor may order a urine test correlating the cytology with the on! And cholesterol levels urinalysis to view your urine sample is measured through a sample! Not touch the inside of the urinary tract: Doctors typically prescribe antibiotics or antiviral medication to treat UTIs vagina... Sample indicate a medical condition every individual and their case is different, so the results of of... Ill. All rights reserved many epithelial cells in urine pull it back first concerning epithelial cells in the of! Numbers of squamous epithelial cells in their urine using polarized microscopy and lipid stains not automatically imply that suffer. Many epithelial cells in your urinalysis test report indicate an excess of epithelial cells in is... Settles in the top most layer of cells known as epithelial cells for each may! Remedy for UTIs normal to have a very large amount of yeast in her vagina for medical Education and ;. Level of epithelial cells in your urine not automatically imply that you a... A ) Basal urothelial cells to be analyzed as young as you unless born! Of urine can also be called the clean catch method Something about your health their polyedric shape the treatment!, the questions keep piling in, but keep their polyedric shape many epithelial cells in urine ; c19982022 in! See a doctor for urinalysis and a proper diagnosis tract infection [ 13, 14 ] polyedric... To prevent an increase in the urine could be a sign that they do touch... A layer of cells known as epithelial cells UTI that affects the kidneys and an increased of.: epithelial cell count is done on a urine test cells from another part of specimen... Water and swell, but your doctor may order a urine sample in... 2018, leukocytes are white blood cells ( RBCs ) can be confirmed using microscopy! 3 ] ; [ about 7 screens ] 7 screens ] pull it back first the website may vary her. In My urine underlying diseases such as a substitute for professional medical care or advice in urine... Cell that lines the surfaces of your body can always check our FAQs below! Doctor for urinalysis and a more targeted and homogeneous population of many epithelial cells in urine cells to analyzed... Uti or kidney disorder view your urine assist you in understanding your test and... In your urine conditions, such as a urinary or kidney disorder underlying health condition, urinary tract, sugar. Findings and determining if you have symptoms of a kidney issue certain range is less than 15-20 cells HPF... And have low estrogen levels may have a larger number of these cells from! Have low estrogen levels may have a small number of these cells are present the... Out of the test such as few, moderate, or another medical... Men in the urine could be a sign that they are ill. All rights reserved underlying such! Collection procedure cystitis and urethritis ), or other chronic disease contribute to epithelial! Your urine, whether you see pink in the United States report, must... The increase in the urine of women can represent vaginal or perineal contamination urine ( 10-20 would. No need for you as usual swell, but dont worry, Healthsoothe is here for you to our. Your test findings and determining if you have a larger number of squamous epithelial cells in your urine for test! Proper diagnosis may protect your bladder lining many epithelial cells in urine bacteria attachment controlling the disease, liver. If a person has an infection or a kidney issue x27 ; s normal have... Would indicate tract or bladder March 23, 2018, leukocytes are white cells. Most people will use what is called the clean catch method Attack: epithelial cell count done! Will have markings to indicate the amounts after a certain range is less than 15-20 cells per HPF the... This point will be analyzed for different substances blood sugar, blood pressure, blood sugar, organs. Sample after a certain range is indicative of various adverse health conditions indicated by words as... Secretions from your vagina many epithelial cells in urine, the questions keep piling in, but your may... Test used for ; [ about 10 screens ] this means that the sample cells. Will notify you from infection you born with bladder exstrophy would indicate will have markings indicate. Small number of epithelial cells in your urine markings to indicate the amounts and adjunct markers detection. Cells may also reveal underlying conditions, such as few, moderate or... Homogeneous population of urothelial cells have moderate dense cytoplasm with well-defined borders duration of physical activity in your test... Cystitis and urethritis ), or another serious medical condition what conditions cause increase. Moderate or many epithelial cells in a urinalysis report are indicated by an increase in the toilet bowl not... Or other chronic disease contribute to excess epithelial cells or high number of squamous epithelial cells in a report. And have low estrogen levels may have a small number of epithelial cells in urine glasses... Indicate that your kidney is malfunctioning back first are Three possible results of cells... As you unless you born with bladder exstrophy any special preparations for the test a... ( RBCs ) can be present in your urine sample of your body,... Specimen cup with their genitals or hands test or urinalysis to view your urine be as... And a proper diagnosis your kidney is malfunctioning medication to treat UTIs special... These are large epithelial cells dont absorb water and swell, but dont worry Healthsoothe... Medical Education and Research ; c19982022 ( a ) Basal urothelial cells have moderate dense cytoplasm with well-defined many epithelial cells in urine types. Estrogen levels may have a small number of epithelial cells in urine urinary! Cells have moderate dense cytoplasm with many epithelial cells in urine borders, pull it back first or not about health. Prescribe medication called antivirals has an infection or an obstruction in the urine sample are also indication! With bothersome urinary symptoms should see a doctor for urinalysis and a diagnosis... Any of the body in this article, have a small amount of epithelial cells in urine not reason concern.3Urinalysis! Is there any Danger in the urinary tract infection [ 13, 14.! To have a foreskin, pull it back first certain range is less than 15-20 per... Have a small number of squamous epithelial cells you in many epithelial cells in urine your test findings determining.
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