Forward-looking statements include, among other things, statements about the potential benefits of the proposed transaction; the prospective performance and outlook of Five Prime's business, performance and opportunities; any potential strategic benefits, synergies or opportunities expected as a result of the proposed transaction; the ability of the parties to complete the proposed transaction and the expected timing of completion of the proposed transaction; potential marketing or regulatory approvals for bemarituzumab, or potential future revenues from such product; as well as any assumptions underlying any of the foregoing. THESE MATERIALS WILL CONTAIN IMPORTANT INFORMATION ABOUT THE TENDER OFFER, FIVE PRIME AND AMGEN. Annual report [Section 13 and 15(d), not S-K Item 405] SEC.report. Food and Drug Administration. News release. The length of time that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past varied and we expect similar variability in the future. These filings show these funds' portfolio positions as of March 31st, 2020. About the FIGHT TrialThe FIGHT study was a randomized, placebo controlled trial that evaluated bemarituzumab plus chemotherapy (mFOLFOX6) versus placebo plus chemotherapy in patients with fibroblast growth factor receptor 2b-positive (FGFR2b+), non HER2 positive frontline advanced gastric or GEJ cancer. Drugs approved for stomach (gastric) cancer. At the moment there are many gauges stock market investors can use to value publicly traded companies. Information regarding presentation times, webcast availability and webcast links are noted onAmgen's Investor Relations Events Calendar. All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of the Five Prime Therapeutics, Inc. acquisition, as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems such as the ongoing COVID-19 pandemic on our business. Seed, Series A, Private Equity), Whether an Organization is for profit or non-profit, General contact email for the organization, Auto-generated name of transaction (e.g. Hourly rate can vary widely depending on many important factors, including education, certifications, additional skills, the number of . View table here if you experience formatting issues. The bemarituzumabPhase 2 FIGHT trial demonstrated clinically meaningful improvements in progression-free survival (PFS), overall survival (OS) and overall response rate (ORR) in the frontline treatment of patients with advanced gastric or GEJ cancer. Five Prime Therapeutics, Inc. provides clinical stage biotechnology services. Were here to answer your questions. CONTACT: Amgen, Thousand OaksMegan Fox, 805-447-1423 (media)Trish Rowland, 805-447-5631(media)Arvind Sood, 805-447-1060 (investors), Five Prime Media and Investor ContactMartin Forrest, 415-365-5625, View original content to download multimedia:http://www.prnewswire.com/news-releases/amgen-to-acquire-five-prime-therapeutics-for-1-9-billion-in-cash-301240358.html. FIVE PRIME THERAPEUTICS, INC. : FPRX Stock Price | US33830X1046 | MarketScreener Homepage Equities United States Nasdaq Five Prime Therapeutics, Inc. Summary FPRX US33830X1046 FIVE PRIME THERAPEUTICS, INC. (FPRX) Add to my list Summary Quotes Charts News Ratings Company Funds Free and open company data on California (US) company FIVE PRIME THERAPEUTICS, INC. (company number 2375010), 111 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080 Five Prime Therapeutics Inc - AnnualReports.com Ticker FPRX Exchange NASDAQ More Industry Biotechnology More Sector Healthcare More 51-200 Employees Based in San Francisco, California Most Recent Annual Report MOST RECENT 2020 Form 10K, 2019 Annual Report Report Locked. The company's also offer eligible shareholders the opportunity to acquire up to A$30,000 of new shares through a . There can be no guarantee that the proposed tender offer or the transaction described in this press release will be completed, or that it will be completed as currently proposed, or at any particular time. Transaction Terms Under the terms of the merger agreement, which was approved by the Boards of Directors of both companies, Amgen will commence a tender offer to acquire all of the outstanding shares of Five Prime's common stock for $38.00 per share in cash. Treatment related adverse events of grade 3 or higher occurred in 63 patients (82.9%) in the bemarituzumab arm and 57 patients (74%) in the placebo arm. [table] Ticker, No of HFs with positions, Total Value of HF Positions (x1000), Change in HF Position ESCA,3,5879,0 PLG,3,3650,0 HIL,10,26366,-3 MNTX,7,7980,1 Average,5.75,10969,-0.5 [/table]. Five Prime Therapeutics Revenue $13.2 M FY, 2020 Company summary Overview Five Prime Therapeutics is a biotechnology company focused on developing immuno-oncology and targeted cancer therapies. Our business may be impacted by government investigations, litigation and product liability claims. Clinical Trial Diversity and Representation, Clinical Trial Transparency, Data Sharing and Disclosure Practices, Adverse Event and Product Complaint Reporting, Environmental, Social & Governance Report 2021, Environment, Social and Governance Strategy, Community Investment and Amgen Foundation, Amgen To Acquire Five Prime Therapeutics For $1.9 Billion in Cash, https://investors.amgen.com/financials/sec-filings, https://investor.fiveprime.com/index.php/sec-filings, https://www.cancer.gov/about-cancer/treatment/drugs/stomach#1, http://www.prnewswire.com/news-releases/amgen-to-acquire-five-prime-therapeutics-for-1-9-billion-in-cash-301240358.html. The stock is currently up 123.4% year-to-date, up 889.6% over the past 12 months, and up 10.0% over the past five years. THE TENDER OFFER MATERIALS (INCLUDING AN OFFER TO PURCHASE, A RELATED LETTER OF TRANSMITTAL AND OTHER OFFER DOCUMENTS) AND THE SOLICITATION/RECOMMENDATION STATEMENT WILL CONTAIN IMPORTANT INFORMATION THAT SHOULD BE READ CAREFULLY WHEN THEY BECOME AVAILABLE AND CONSIDERED BEFORE ANY DECISION IS MADE WITH RESPECT TO THE TENDER OFFER. Our employees are dedicated to improving health outcomes, creating a better member experience and lowering the total cost of care. Five Prime Therapeutics, Inc. 4 years 10 months Director, Immuno-Oncology Research Five Prime Therapeutics, Inc. Aug 2017 - Jan 2019 1 year 6 . Unless otherwise noted, Amgen is providing this information as of the date of this news release and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise. Exploring benefit solutions? About BemarituzumabBemarituzumab (anti-FGFR2b) is a first-in-class targeted antibody that blocks fibroblast growth factors (FGFs) from binding and activating FGFR2b, inhibiting several downstream pro-tumor signaling pathways and potentially slowing cancer progression. BOSTON, Jan. 06, 2023 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. ("Compass"; Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases, today announced that the first patient has been dosed in the Phase 2 U.S. study of CTX-009 in patients with metastatic colorectal cancer who are being . Five Prime Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of protein therapeutics that block cancer and inflammatory disease processes. Assignee: Five Prime Therapeutics, Inc. Goldman Sachs acted as financial advisor to Amgen and Sullivan & Cromwell LLP as its legal advisor. Amgen has completed its planned acquisition of Five Prime Therapeutics for $38.00 per share in cash, or approximately $1.9 billion. Furthermore, you'd generally like to see the share price rise faster than the market. For the last four decades, we have been dedicated to discovering the firsts that matter in oncology and to finding ways to reduce the burden of cancer. To build a better tomorrow for people with cancer, we are teaming up with patients, physicians, scientists, and industry partners to make a meaningful difference in patients' lives. Release Summary. Bray F, Ferlay J, Soerjomataram I, et al: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. After seeing the biotech's shares soar 300% late last year on positive new data for its midstage gastric cancer program, Amgen has stepped in with a $1.9 billion deal to buy out l Need a pharmacy resource? View contacts for Five Prime Therapeutics to access new leads and connect with decision-makers. amgen has completed its planned acquisition of five prime therapeutics for $38.00 per share in cash, or approximately $1.9 billion. FivePrime is a clinical-stage biotechnology company that develops treatments for cancers. Amgen reaffirmed its full-year outlook with Revenue guidance of $25.8 to $26.6 billion and non-GAAP EPS guidance of $16.00-$17.00. Amgen. Building on our heritage, Amgen continues to advance the largest pipeline in our history, moving with great speed to advance those innovations for the patients who need them. Romaine Bostick breaks down the day's top stories and trading action leading into the close. If we fail to meet the compliance obligations in the corporate integrity agreement between us and the U.S. government, we could become subject to significant sanctions. "We look forward to welcoming the Five Prime team to Amgen and working with them to leverage our best-in-class monoclonal antibody manufacturing capabilities to supply additional clinical materials, as well as expanded production quantities, to realize the full potential of bemarituzumab for even more patients around the world as quickly as possible. Accessed April 19, 2021. Five Prime Therapeutics granted an exclusive license to Zai Lab Limited to develop and commercialize bemarituzumab in Greater China, and Zai Lab collaborated with Five Prime Therapeutics on the Phase 2 FIGHT trial in Greater China. stage for pigmented villonodular synovitis and multiple cancers in combination with nivolumab. Five Prime collaborates with leading global pharmaceutical companies and has therapies in pre-clinical and clinical development. This vision is what defines us and guides our research, clinical development and partnerships. Median OS in the bemarituzumab arm was not reached at the data cutoff (95% CI, 13.8not reached) compared with 12.9 months (95% CI, 9.1-15.0) for the placebo/mFOLFOX6 arm (HR, 0.58; 95% CI, 0.35-0.95; P = .0268). from 8 AM - 9 PM ET. Lazard acted as financial advisor to Five Prime and Cooley LLP as its legal advisor. Our efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful. THOUSAND OAKS, Calif., April 16, 2021 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that it has successfully completed its previously announced tender offer to purchase all outstanding shares of common stock of Five Prime Therapeutics (NASDAQ:FPRX), a clinical-stage biotechnology company focused on developing immuno-oncology and targeted cancer therapies, for $38.00 per share in cash. Results from the phase 2 FIGHT trial (NCT03694522) showed positive results in patients with previously untreated advanced gastric or GEJ cancer who were HER2 negative. Check out new products, client successes, community activity, and more. This correlation suggests that FGFR2b could play a role in other epithelial cancers, including lung, breast, ovarian and other cancers. Goldman Sachs acted as financial advisor to Amgen and Sullivan & Cromwell LLP as its legal advisor. Five Prime Therapeutics Inc (NASDAQ: FPRX) has seen a decrease in activity from the world's largest hedge funds recently. pdf 18-00253-t.pdf (436.22 KB) Modified: July 21, 2022 STAY CONNECTED 1 Twitter 2 Facebook 3 RSS 4 YouTube 6 LinkedIn 8 Email Updates. William Ringo - Chairman and interim CEO. November 11, 2020 05:45 PM Eastern Standard Time. Important InformationThis press release is for informational purposes only and is neither an offer to purchase nor a solicitation of an offer to sell securities. Following the completion of the tender offer, a wholly-owned subsidiary of Amgen will merge with Five Prime and shares of Five Prime that have not been tendered and purchased in the tender offer will be converted into the right to receive the same price per share in cash as paid in the tender offer (other than shares held by stockholders who properly demand and perfect appraisal rights under Delaware law). Our research drives us to understand the disease in the context of the patient's life not just their cancer journey so they can take control of their lives. Inventors: Thomas Brennan, David Bellovin, David Busha, Barbara Sennino Method of treating gastric cancer with anti-FGFR2-IIIb antibodies and modified FOLFOX6 chemotherapy Patent number: 11091555 2023 Prime Therapeutics LLC, All Rights Reserved. EcoR1 Capital is also relatively very bullish on the stock, designating 0.06 percent of its 13F equity portfolio to FPRX. 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